Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sex-linked Disorders01:43

Sex-linked Disorders

108.1K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
108.1K
Teratogenicity01:07

Teratogenicity

3.9K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.9K
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

1.3K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
1.3K
Pedigree Analysis01:35

Pedigree Analysis

88.7K
Overview
88.7K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.2K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.2K
Integrated Healthcare System01:20

Integrated Healthcare System

2.2K
An integrated healthcare system (IHS) is a set of organizations that provides for or arranges to provide coordinated and continuous service to a defined population. The IHS takes responsibility for that particular population's health status and outcome, both clinically and fiscally. An integrated healthcare system is a well-organized, well-coordinated, and collaborative network. The integrated delivery system is a network that connects different healthcare providers to deliver organized,...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 2, Regulatory and Safety Considerations.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 3, Marketing of Infant Formulas, Breastfeeding Support, Hypoallergenic Formulas, and Nutrition for Preterm Infants.

Advances in nutrition (Bethesda, Md.)·2026
Same author

V-Cornea: A computational model of corneal epithelium homeostasis, injury, and recovery.

PLoS computational biology·2025
Same author

High-throughput cytokine detection platform for evaluation of chemical induced microglial activation.

SLAS technology·2025
Same author

V-Cornea: A computational model of corneal epithelium homeostasis, injury, and recovery.

bioRxiv : the preprint server for biology·2025
Same journal

Retraction notice to "Trehalose restores functional autophagy suppressed by high glucose" [Reprod. Toxicol. 85 (2019) 51-58].

Reproductive toxicology (Elmsford, N.Y.)·2026
Same journal

Exposure to toxic metals/metalloids in the environment and in vitro fertilization outcomes in a population group from Romania.

Reproductive toxicology (Elmsford, N.Y.)·2026
Same journal

Gadolinium Induces Sertoli Cell Damage: Cellular and Molecular Mechanisms.

Reproductive toxicology (Elmsford, N.Y.)·2026
Same journal

Influence of radiofrequency electromagnetic radiation on spermatogenesis and sperm function in rodent models: A systematic review.

Reproductive toxicology (Elmsford, N.Y.)·2026
Same journal

Microplastics as trojan horses: A new perspective on bisphenol toxicity in male infertility and assisted reproduction.

Reproductive toxicology (Elmsford, N.Y.)·2026
Same journal

Effects of prenatal pyrethroid pesticides exposure on neurodevelopment of 3-year-old children: A birth cohort study in rural Southwest China.

Reproductive toxicology (Elmsford, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Jan 6, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
08:28

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

Published on: March 10, 2020

7.3K

Data input module for Birth Defects Systems Manager.

Kenneth B Knudsen1, Amar V Singh, Thomas B Knudsen

  • 1University of Louisville, School of Dentistry, Birth Defects Center, 501 S. Preston St., Louisville, KY 40202, USA.

Reproductive Toxicology (Elmsford, N.Y.)
|June 1, 2005
PubMed
Summary
This summary is machine-generated.

We developed LoadBDSM, a data loading module for the Birth Defects Systems Manager (BDSM), to manage functional genomics and proteomics data. This bioinformatics infrastructure supports developmental biology and toxicity research, enabling "embryo-formatics" discovery.

More Related Videos

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

13.1K
Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

14.8K

Related Experiment Videos

Last Updated: Jan 6, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
08:28

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

Published on: March 10, 2020

7.3K
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

13.1K
Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
16:23

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

14.8K

Area of Science:

  • Bioinformatics
  • Developmental Biology
  • Toxicology

Background:

  • Functional genomics and proteomics generate vast amounts of digital data.
  • Existing bioinformatics infrastructure is insufficient for managing this data in developmental biology and toxicology.
  • There is a need for specialized systems to facilitate analysis and discovery in these fields.

Purpose of the Study:

  • To describe the design, development, and implementation of LoadBDSM, the data loading module for the Birth Defects Systems Manager (BDSM).
  • To create an open resource for managing and analyzing developmental biology and toxicity data.
  • To support the emerging field of "embryo-formatics".

Main Methods:

  • Developed LoadBDSM as a data loading module for BDSM.
  • Implemented a shared data directory with customizable security levels.
  • Enabled data upload using controlled semantics for exposure, biological samples, and disease outcomes.
  • Adhered to existing controlled vocabularies and ontologies for data annotation.

Main Results:

  • LoadBDSM facilitates the upload of experimental data and details with controlled semantics.
  • The system supports secure, group-based management of experimental datasets.
  • LoadBDSM integrates with BDSM to enhance data analysis capabilities.
  • The module supports the annotation of experiments, data, and metadata using ontologies.

Conclusions:

  • LoadBDSM is a robust data loading module that enhances the BDSM platform.
  • This system facilitates "embryo-formatics" by integrating genomic sciences with embryological data.
  • It enables advanced analyses such as pathway delineation, biomarker development, and data integration for developmental toxicity research.