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Radiotherapy and radiosurgery for benign neurofibromas
Rahul Chopra1, Christopher G Morris, William A Friedman
1Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610-0385, USA.
American Journal of Clinical Oncology
|June 1, 2005
Summary
Radiotherapy (RT) and stereotactic radiosurgery (SRS) effectively control neurofibromas. These treatments offer local tumor control with no significant complications for patients unsuitable for surgery.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Neurofibromas are benign tumors that can cause significant morbidity.
- Surgical resection is the primary treatment, but not always feasible.
- Alternative treatment options are needed for unresectable neurofibromas.
Purpose of the Study:
- To evaluate the efficacy of radiotherapy (RT) and stereotactic radiosurgery (SRS) for treating neurofibromas.
- To assess the safety and effectiveness of non-invasive treatment modalities for neurofibroma management.
Main Methods:
- Retrospective study of 4 patients with neurofibromas.
- Treatment administered included conventional radiotherapy (RT) or stereotactic radiosurgery (SRS).
- Patient follow-up ranged from 1.7 to 14.8 years.
Main Results:
- Complete local tumor control was achieved in all treated patients.
- No significant treatment-related complications were observed.
- Both RT and SRS demonstrated favorable safety and efficacy profiles.
Conclusions:
- Radiotherapy and stereotactic radiosurgery are effective treatment options for neurofibromas.
- These modalities provide durable local control for patients who are not candidates for surgical resection.
- RT and SRS represent valuable therapeutic strategies for managing complex neurofibroma cases.