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Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
Published on: February 3, 2014
[Single plane Simpson's method for measurement of right ventricular volume by X-ray ventriculography]
Wei Cui1, Zhi-Qun Han, Yan-Guang Feng
1Department of Cardiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Objective:
To study the validity of single plane Simpson's method with conventional X-ray ventriculography for estimation of right ventricular (RV) volume.
Methods:
Fifteen human RV casts were obtained from 15 subjects who died from non-cardiac causes within 24 hours after death. These casts were photographed respectively and their volumes were calculated by using the single plane Simpson's method based on a new half-circle model. The actual RV cast volumes were determined by water displacement method.
Results:
The actual RV volume was (64.23 +/- 24.51) ml and the calculated volume was (58.04 +/- 24.45) ml. The calculated RV volume underestimated the actual volume by (6.19 +/- 12.38) ml, but there was no significant difference between the actual and the calculated RV volume (P > 0.05). There was a significant correlation between the actual cast volume and the calculated volume (r = 0.983, P < 0.01). The regression equation was: RV actual volume = 1.074 x (RV calculated volume).
Conclusion:
RV volume calculated by single plane Simpson's method with conventional X-ray ventriculography is accurate and deserves further study.
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