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Rhinocerebral mucormycosis: perineural spread via the trigeminal nerve

Sebnem Orguc1, Ali Vefa Yücetürk, M Akif Demir

  • 1Department of Radiology, Celal Bayar University, Medical Faculty, Manisa, Turkey. sebnemorguc@superonline.com

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|June 1, 2005
PubMed

Insights

Rhinocerebral mucormycosis can spread to the brainstem via the trigeminal nerve, causing a pontine abscess. Magnetic resonance imaging (MRI) effectively visualized this rare perineural disease progression.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Rhinocerebral mucormycosis is a rare, aggressive fungal infection.
  • Involvement of the central nervous system is uncommon but serious.

Observation:

  • A case of rhinocerebral mucormycosis presented with an abscess in the lateral pons.
  • Perineural spread along the trigeminal nerve was identified as the likely pathway.

Findings:

  • Contrast-enhanced MRI demonstrated the extent of the fungal infection and perineural spread.
  • Pathological diagnosis was confirmed via rhino-orbital punch biopsy.

Implications:

  • Highlights the potential for unusual spread patterns in mucormycosis.
  • Emphasizes the utility of advanced imaging in diagnosing complex infections.
  • Underscores the importance of early recognition and biopsy for definitive diagnosis.

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