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Isolation, Transfection, and Culture of Primary Human Monocytes
Published on: December 16, 2019
[Cells of the immune system in the pathogenesis of HIV infections.]
Venuse Skokanová1, Marie Stanková
1Department Of Immunology, Regional Institute Of Public Health Kolín, Office Prague, Czech Republic.
Abstract:
For more than twenty years comprehensive research has been focusing on the pathogenesis of HIV infections. In this multifactorial complex a crucial role is played, in addition to virological aspects, by the mechanisms of the host's immune system. The paper focuses primarily on the role of T lymphocytes and of antigen - presenting cells - macrophages and dendritic cells - in HIV infections. It also discusses the control of HIV infections using neutralizing antibodies and HIV-1 specific CD8+ cytotoxic T lymphocytes and CD4+ T lymphocytes.
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