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Updated: Aug 17, 2026
Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles
Published on: October 15, 2014
Gray characteristic analysis of microtubules in cardiac myocytes
Yu-hua Yao1, Jiang-hui Xiong, Zhong-gang Liang
1Institute of Space Medico-Engineering, Beijing.
Objective:
To quantify the images of the microtubules in fetal rat cardiac myocytes under simulated microgravity by utilizing the characteristic parameters of image gray, and to study their morphological change.
Method:
Gray characteristic of the microtubules in fetal rat cardiac myocytes was quantified in both simulated microgravity and control conditions by variance, skewness, and kurtosis.
Result:
From feature analysis of 24 images, the characteristic parameters selected here were proved to be effective. Good result was obtained when discrimination between simulated microgravity group and control group was made by multivariate analysis with these parameters. The total false verdict rate even reached 16.7% when using multivariate analysis with these parameters.
Conclusion:
The morphology of the microtubules in cardiac myocytes cytoskeleton became diffused under simulated microgravity, and the quantitative analysis of gray parameters (variance, skewness, kurtosis) described the variation satisfactorily.
