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Updated: Aug 17, 2026
Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
[Effects of intermittent normobaric hypoxia training on heart rate variability]
Xin Xu1, Li-li Lu, Zhang-huang Chen
1Institute of Space Medico-Engineering, Beijing, China.
Objective:
To observe the influences of intermittent normobaric hypoxia (INH) training on heart rate variability (HRV) under hypoxia.
Method:
Eight subjects were trained with INH for 4 weeks (24 d), subjects' HRV level, recorded during exposure to hypoxia (10% O2) before and after the training, were compared and analyzed.
Result:
After the INH training, average of normal to normal Intervals (R-R), standard deviation of normal to normal Intervals (SDNN), total power (TP), high frequency (HF) and low frequency (LF) increased significantly during hypoxia (P<0.05 - P<0.001); normalized low frequency (LFn), normalized high frequency (HFn) and LF/HF showed no significant change.
Conclusion:
1) INH training can increase subjects' HRV under hypoxia; 2) INH training can not only be used to increase the tolerance of hypoxia, but it is also good for increasing astronaut's flying tolerance under special environment.
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