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Published on: November 21, 2017
[Infants aged 3-24 months with fever without source in the emergency room: characteristics, management and outcome]
S Mintegi Raso1, M González Balenciaga, A Pérez Fernández
1Urgencias de Pediatría, Hospital de Cruces, 48903 Baracaldo, Bilbao, España. smintegui@hcru.osakidetza.net
Insights
Fever without source in infants aged 3-24 months is common in emergency rooms. Nearly 30% of these children have a different final diagnosis, with 12% requiring antibiotics.
Area of Science:
- Pediatrics
- Emergency Medicine
- Infectious Disease
Context:
- Fever without source (FWS) is a frequent reason for pediatric emergency room (ER) visits in infants.
- Accurate and timely diagnosis of FWS is crucial for appropriate management and preventing adverse outcomes.
- Understanding the characteristics and outcomes of infants with FWS informs clinical practice and resource allocation in ER settings.
Purpose:
- To characterize infants aged 3-24 months presenting with FWS to a pediatric ER.
- To analyze the management strategies employed for these infants.
- To determine the subsequent outcomes and diagnostic accuracy for FWS in this age group.
Summary:
- A retrospective survey of 733 infants (3-24 months) with FWS revealed that 92.3% were initially diagnosed with FWS.
- Diagnostic workup, including complete blood count and blood culture, was influenced by age, fever duration, and temperature.
- In outpatients initially diagnosed with FWS, the final diagnosis differed in 27.5% of cases, with 12.1% ultimately receiving antibiotics.
Impact:
- The study highlights the diagnostic uncertainty in infants with FWS, emphasizing the need for careful observation and reassessment.
- Findings suggest that nearly 30% of initial FWS diagnoses are revised, impacting treatment decisions and potentially leading to unnecessary antibiotic use.
- This research underscores the importance of robust follow-up protocols for infants presenting with FWS to the ER.
Objective:
To determine the characteristics of infants aged 3-24 months admitted to a Hospital Pediatric Emergency Room with fever without source, the management of these infants and their subsequent outcome.
Patients And Method:
We performed a retrospective survey of 733 children aged 3-24 months with fever without source admitted to our Emergency Room between September 1, 2003 and December 31, 2003. Subsequently, the parents of all infants diagnosed with fever without source who were managed as outpatients were telephoned to ascertain their outcome and changes in the final diagnosis.
Results:
Onset of fever occurred less than 6 hours before arrival at the hospital in 237 episodes (32.2%). The family reported a temperature of > or = 39 degrees C in 436 episodes. Diagnoses in the Emergency Room were the following: fever without source in 677 (92.3%), urinary tract infection in 53 (7.2%) and bacterial meningitis in three (0.4 %). Fifty-five infants with an altered dipstick were excluded and complete blood count (CBC) and blood culture were performed in 66 infants (9.7%). There was a significant negative association between the probability of a request for CBC and blood culture and higher age [6-11 months vs. 3-6 months OR 0.24 (95 % CI: 0.11-0.49); > or = 12 months vs. 3-6 months, OR 0.15 (0.07-0.3)] and a significant positive association with onset more than 12 hours previously [vs. less than 6 hours OR 2.3 (1.2-4.43)] and highest temperature registered at home > 40 degrees C [vs. less than 39 degrees C OR 4.22 (1.5-11.84)]. Follow-up was completed (by telephone or readmission to the Emergency Room) in 574 infants diagnosed with fever without source and managed as outpatients. The final diagnosis differed from that made in the Emergency Room in 158 infants (27.5%), and 70 received antibiotics (12.1%).
Conclusions:
A considerable percentage of infants aged 3-24 months with fever without source visits the Emergency Room with very short-term processes. Patient observation is very useful in the management of these infants, since the final diagnosis differed from that made in the emergency room in nearly 30% and 12% were treated with antibiotics.
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