[Subureteral polydimethylsiloxane injection for the endoscopic treatment of vesicoureteral reflux]

C Soto Beauregard1, F Rivilla Parra, J García Casillas

  • 1Servicio de Cirugía Pediátrica, Hospital Universitario San Carlos, 28040 Madrid, España. msoto.hcsc@salud.madrid.org

Insights

Endoscopic subureteral polydimethylsiloxane injection effectively treats pediatric vesicoureteral reflux (VUR) with low morbidity. This minimally invasive procedure offers a safe and well-tolerated option for managing VUR in children.

Area of Science:

  • Pediatric Urology
  • Minimally Invasive Surgery
  • Biomaterials in Medicine

Context:

  • Vesicoureteral reflux (VUR) is a common condition in children, increasing the risk of urinary tract infections and kidney damage.
  • Traditional open surgery for VUR can be invasive, carrying risks of significant morbidity.
  • Endoscopic subureteral injection offers a less invasive alternative for VUR treatment.

Purpose:

  • To evaluate the effectiveness, long-term follow-up, and morbidity of subureteral polydimethylsiloxane injection for treating pediatric VUR.
  • To assess the success rates of single and multiple polydimethylsiloxane injections.
  • To identify factors influencing treatment outcomes.

Summary:

  • A study of 28 children with VUR treated with endoscopic subureteral polydimethylsiloxane injection showed an 86% success rate after one or two injections.
  • Mean follow-up was 18 months, with low morbidity reported.
  • Factors such as reflux grade and implant characteristics influenced effectiveness.

Impact:

  • Subureteral polydimethylsiloxane injection is a simple, well-tolerated procedure with low morbidity for pediatric VUR.
  • This technique can be successfully applied to complex cases, including bilateral VUR.
  • The findings support endoscopic subureteral injection as a viable treatment option, potentially reducing the need for open surgery.
Abstract

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