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Related Experiment Video

Updated: Jul 18, 2026

Fat Preference: A Novel Model of Eating Behavior in Rats

Fat Preference: A Novel Model of Eating Behavior in Rats

Published on: June 27, 2014

Calcium deficiency cannot induce obesity in rats.

S Paradis¹, M Cabanac

¹Département d'anatomie et physiologie, Centre de recherche sur le métabolisme énergétique (CREME), Université Laval, Québec, Canada, G1K 7P4.

Physiology & Behavior

|June 2, 2005

Summary

This study found that low calcium intake in rats did not cause obesity or alter their body weight set-point. Therefore, calcium intake likely does not influence body weight regulation.

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Area of Science:

Nutritional Science
Obesity Research
Physiology

Background:

Calcium is a vital nutrient, and its role in body weight regulation is debated.
Some theories suggest high calcium intake may have an 'anti-obesity' effect by lowering the body weight set-point.

Purpose of the Study:

To investigate the influence of calcium intake on body weight regulation in rats.
To determine if calcium deficiency affects the body weight set-point and leads to obesity.

Main Methods:

Rats were fed diets with varying calcium content for six weeks.
Measurements included body weight, BMI, fat content, plasma calcium, body weight set-point, food intake, and calcium solution preference.
Effects were assessed after the initial period and after a six-week recovery on a standard diet.

Main Results:

Low calcium intake induced deficiency but did not increase the body weight set-point.
Obesity and increased fat accumulation were not observed in calcium-deprived rats.
Body weight and fat content returned to normal levels after recovery, comparable to control and supplemented groups.

Conclusions:

Calcium deprivation in rats did not result in obesity or an elevated body weight set-point.
The findings suggest that dietary calcium intake does not significantly impact body weight regulation.