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Related Experiment Videos

Response to nocturnal alarms using a real-time glucose sensor.

Bruce Buckingham1, Jen Block, Jonathan Burdick

  • 1Stanford University School of Medicine, Stanford, California 94305-5208, USA. buckingham@stanford.edu

Diabetes Technology & Therapeutics
|June 3, 2005
PubMed
Summary

Children with type 1 diabetes awoke to 66% of alarm events from their glucose monitoring devices. While all confirmed hypoglycemia events woke subjects, many false alarms occurred.

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Area of Science:

  • Pediatric Endocrinology
  • Biomedical Engineering
  • Sleep Medicine

Background:

  • Type 1 diabetes management requires continuous glucose monitoring.
  • Alarms for hypo- and hyperglycemia are crucial for patient safety.
  • Understanding patient response to alarms during sleep is vital.

Purpose of the Study:

  • To evaluate the response of children with type 1 diabetes to hypo- and hyperglycemia alarms during sleep.
  • To assess the audibility and effectiveness of glucose monitoring alarms in pediatric patients.

Main Methods:

  • Twenty pediatric subjects (4-17 years) with type 1 diabetes participated.
  • Continuous glucose monitoring data and video recordings were collected over ~24 hours.
  • Alarm events were defined and subject responses to audible alarms were documented.

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Main Results:

  • 75% of 240 alarms occurred during sleep, with 68% being audible.
  • Subjects awoke to 29% of individual alarms and 66% of alarm events.
  • Younger children (4-6 years) had lower response rates (17%) compared to adolescents (53%).
  • All confirmed hypoglycemia events (< or = 70 mg/dL) resulted in awakening.
  • 55% of alarm events were associated with false alarms (no confirmed hypo- or hyperglycemia).

Conclusions:

  • Children with type 1 diabetes respond to a significant portion of glucose monitoring alarm events during sleep.
  • Confirmed hypoglycemia reliably elicits a response, but false alarms are common.
  • Age influences alarm response rates, with younger children and parents showing lower awareness.