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Endobronchial pseudo-tumour caused by herpes simplex.
A Upadya1, L Tilluckdharry, C D Nagy
1Bridgeport Hospital, Yale-New Haven Health, 267 Grant Street, Bridgeport, CT 06610-0120, USA. paupad@bpthosp.org
The European Respiratory Journal
|June 3, 2005
Summary
Herpes simplex virus type I can cause endobronchial tumors. This case study details a rare instance of HSV-1 presenting as a tumor in a patient with respiratory failure.
Area of Science:
- Pulmonology
- Infectious Diseases
- Pathology
Background:
- Herpes simplex virus (HSV) commonly causes tracheobronchitis and pneumonitis.
- Endobronchial masses are rare manifestations of HSV infections, with only one prior report of HSV type II.
Observation:
- A 68-year-old female with severe kyphoscoliosis developed blood-tinged endotracheal secretions after intubation for respiratory failure.
- Fibreoptic bronchoscopy revealed an endobronchial mass in the right middle lobe.
Findings:
- Cultures confirmed Herpes simplex virus type I (HSV-1) infection.
- Biopsy specimens showed cytopathological changes consistent with HSV infection.
Implications:
- This is the first reported case of HSV type I presenting as an endobronchial tumor.
- Highlights the potential for HSV-1 to cause unusual respiratory tract pathology.
- May prompt consideration of HSV in the differential diagnosis of endobronchial masses.