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Related Experiment Videos

Apraxia in movement disorders.

Cindy Zadikoff1, Anthony E Lang

  • 1Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

Brain : a Journal of Neurology
|June 3, 2005
PubMed
Summary
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Apraxia, a skilled motor disturbance, is challenging to diagnose alongside other movement disorders like bradykinesia. Corticobasal degeneration often features apraxia, impacting daily function.

Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Apraxia is defined as a disturbance in skilled motor performance not attributable to elemental motor deficits.
  • Diagnosing limb-kinetic apraxia is complicated by co-occurring movement disorders like bradykinesia and dystonia.
  • The nomenclature for apraxic syndromes is inconsistent, with terms like 'gait apraxia' potentially being misnomers.

Purpose of the Study:

  • To clarify the diagnostic challenges of apraxia, particularly limb-kinetic apraxia, in the presence of other motor disorders.
  • To review the role of apraxia in corticobasal degeneration (CBD) and related syndromes.
  • To discuss the impact of apraxia on functional disability in various neurological conditions.

Main Methods:

  • Literature review and synthesis of existing research on apraxia and movement disorders.

Related Experiment Videos

  • Analysis of clinical-pathological correlates and functional imaging studies.
  • Clinical evaluation of apraxia in patients with corticobasal syndrome (CBS), progressive supranuclear palsy (PSP), and Parkinson's disease.

    • Main Results:

    • Apraxia is a key feature of CBD, manifesting as ideomotor and limb-kinetic apraxia.
    • Corticobasal syndrome (CBS) can be caused by various pathologies including PSP and Alzheimer's disease.
    • Apraxia and movement disorders often involve widespread cerebral cortical and basal ganglia structures, complicating evaluation.

    Conclusions:

    • Distinguishing apraxia from elemental motor disorders is crucial for accurate diagnosis.
    • While apraxia significantly impacts CBS patients, the contribution of milder forms to daily disability requires further investigation.
    • Inconsistent terminology and overlapping pathologies necessitate careful clinical assessment and research in apraxia.