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Video capsule endoscopy in inflammatory bowel disease 2005
Peter Legnani1, Asher Kornbluth
1The Henry D. Janowitz Division of Gastroenterology, The Mount Sinai Medical Center, New York, New York 10128, USA. plegmd@aol.coom
Current Opinion in Gastroenterology
|June 3, 2005
Summary
Wireless video capsule endoscopy offers a high diagnostic yield for Crohn's disease, improving patient management. Further studies are needed to confirm its exact role and safety in established cases.
Area of Science:
- Gastroenterology
- Medical Technology
- Diagnostic Imaging
Background:
- Crohn's disease diagnosis relies on clinical history, physical exam, radiography, and ileocolonoscopy.
- Wireless video capsule endoscopy provides direct visualization of the small bowel mucosa.
Purpose of the Study:
- To review recent studies on capsule endoscopy for Crohn's disease.
- To assess its diagnostic yield, impact on management, and outcomes.
- To review safety issues, including capsule retention.
Main Methods:
- Review of recently reported studies on capsule endoscopy in Crohn's disease.
- Analysis of diagnostic yield, management impact, and outcomes.
- Evaluation of safety data, focusing on capsule retention.
Main Results:
- Capsule endoscopy shows diagnostic yields over 70% for Crohn's disease in patients with inconclusive prior tests.
- It is more sensitive than radiography, but specificity and positive predictive values require further establishment.
- Capsule retention rates are low (<1%) in suspected cases but higher (4-6%) in established Crohn's disease.
Conclusions:
- Capsule endoscopy is effective for diagnosing and monitoring Crohn's disease.
- Prospective comparative studies with clear endpoints are essential to define its definitive role.