Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Miniaturization in functional genomics and proteomics.

Sascha Sauer1, Bodo M H Lange, Johan Gobom

  • 1Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 73, D-14195 Berlin, Germany. sauer@molgen.mpg.de

Nature Reviews. Genetics
|June 3, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Target ALS Global Natural History Study: Cross-platform proteomics to accelerate biofluid biomarker and drug target discovery in amyotrophic lateral sclerosis.

medRxiv : the preprint server for health sciences·2026
Same author

Prevalence of high-risk plasma p-tau217 levels and 5-year transition of risk status in 70-year-olds.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Real-world performance of Lumipulse G plasma p-tau217: a six-month experience of a specialized clinical neurochemistry laboratory.

Clinical chemistry and laboratory medicine·2026
Same author

Analytical and clinical validation of the Lumipulse G plasma p-tau217 assay for clinical implementation.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Shake and bake: a robust and cost-effective proteomic sample preparation workflow for plasma and cerebrospinal fluid.

Clinical proteomics·2026
Same author

N-Truncated Superoxide Dismutase-1 in Cerebrospinal Fluid Is Folded and Active.

Journal of neurochemistry·2026

Analyzing human proteins and nucleic acids is crucial for understanding disease networks. Technological advancements, including miniaturized biological assays, are needed for high-throughput, low-cost analysis of cellular processes.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Genomics

Background:

  • Proteins are fundamental to cellular machinery, translating genomic information.
  • Understanding protein and nucleic acid interactions is key to decoding complex disease networks.
  • Current technological limitations hinder high-throughput, cost-effective analysis of regulatory processes.

Purpose of the Study:

  • To highlight the importance of analyzing human proteins and nucleic acids.
  • To emphasize the need for technological advancements in biological assay development.
  • To identify miniaturization of biological assays as a critical future direction.

Main Methods:

  • Analysis of human proteins.
  • Analysis of nucleic acids.

Related Experiment Videos

  • Review of current technological capabilities and limitations.

    • Main Results:

    • Human protein and nucleic acid analysis is vital for disease research.
    • Significant technological improvements are necessary for high-throughput, low-cost analysis.
    • Miniaturization of biological assays is identified as a key enabling technology.

    Conclusions:

    • Advancing the analysis of proteins and nucleic acids will improve our understanding of common diseases.
    • Technological innovation, particularly in assay miniaturization, is essential for future progress in molecular biology and genomics.