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Coagulation disorder following viper bite in Orissa
B N Mohapatra1, K Nayak, R N Rath
1Department of Medicine, SCB Medical College, Cuttack.
Journal of the Indian Medical Association
|January 1, 1992
Summary
Viper bites frequently cause bleeding disorders, with disseminated intravascular coagulation being most common. Snake venom antiserum rapidly resolves these issues, though natural recovery is also possible over a longer period.
Area of Science:
- Toxicology
- Hematology
- Clinical Medicine
Background:
- Viper envenomation is a significant medical concern, often leading to severe hemostatic disturbances.
- Coagulation disorders following viper bites can result in serious bleeding complications.
Purpose of the Study:
- To investigate the spectrum of coagulation disorders in viper bite cases.
- To evaluate the efficacy of snake venom antiserum in managing these hematological abnormalities.
Main Methods:
- Retrospective analysis of 43 viper bite cases.
- Clinical assessment of bleeding manifestations and laboratory evaluation of coagulation parameters.
- Monitoring patient response to snake venom antiserum administration.
Main Results:
- 34 out of 43 cases (79.1%) exhibited bleeding from one or more sites.
- Hematuria was the most frequent bleeding manifestation (46.5%).
- Disseminated intravascular coagulation was the predominant coagulation abnormality observed.
Conclusions:
- Viper bites commonly induce significant coagulation disorders and bleeding.
- Snake venom antiserum is effective in achieving prompt recovery from viper bite-induced coagulopathy.
- While natural recovery from coagulation abnormalities can occur, it is a slower process compared to antiserum treatment.