Microorganisms and parasites in chronic infective diarrhea

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Marcellus Simadibrata1, G N J Tytgat, Vera Yuwono

  • 1Department of Internal Medicine, Faculty of Medicine, University of Indonesia.

Acta Medica Indonesiana
|June 4, 2005
PubMed
Abstract

Insights

Pathogenic E. coli and Candida albicans were the most common causes of chronic infective diarrhea in this study. Understanding these microbial patterns is crucial for effective treatment of persistent diarrheal diseases.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Chronic diarrhea affects a significant patient population.
  • Identifying the causative agents of chronic infective diarrhea is essential for targeted therapy.

Purpose of the Study:

  • To elucidate the spectrum of microorganisms responsible for chronic infective diarrhea.
  • To establish the prevalence of various parasitic and bacterial pathogens.

Main Methods:

  • Retrospective analysis of patients diagnosed with chronic infective diarrhea over six years.
  • Comprehensive diagnostic workup including physical examination, laboratory tests, and endoscopic/radiological imaging.

Main Results:

  • Pathogenic Escherichia coli (34.78%) and Candida albicans (48.55%) were the predominant bacterial and parasitic causes, respectively.
  • Other identified pathogens included Blastocystis hominis, Entamoeba histolytica, Giardia lamblia, Aerobacter aerogenes, Mycobacterium tuberculosis, Geotrichum, Shigella sonnei, and Salmonella paratyphi.

Conclusions:

  • Pathogenic E. coli and Candida albicans are the leading infectious agents in chronic diarrhea cases.
  • This study highlights the importance of identifying specific pathogens for managing chronic infective diarrhea.

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