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Updated: Aug 17, 2026
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Published on: June 26, 2013
Three-dimensional stereotactic surface projection study of orthostatic hypotension and brain perfusion image in
1Department of Neurology, Sumitomo Hospital, Nakanoshima, Kita-ku, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp
Objective:
To compare brain perfusion image using three-dimensional stereotactic surface projection (3D-SSP) analysis of N-isopropyl-p-123I iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) between patients with Parkinson's disease with orthostatic hypotension and those without orthostatic hypotension.
Materials And Methods:
Fifteen patients with Parkinson's disease and orthostatic hypotension and 13 patients with Parkinson's disease without orthostatic hypotension were studied. We compared brain perfusion image between the two groups by 3D-SSP.
Results:
Bilateral anterior cingulate gyrus perfusion of the patients with orthostatic hypotension was significantly decreased compared to that of the patients without orthostatic hypotension.
Conclusions:
The disorder of anterior cingulate gyrus may participate in the autonomic failure in Parkinson's disease.
