[Coronary intervention in 1148 patients with chronic total coronary occlusion]

Ya-ling Han1, Jian Zhang, Quan-min Jing

  • 1Department of Cardiology, Shenyang General Hospital, Cardiovascular Research Institute of PLA, Shenyang 110016, China. hanyal@mail.sy.ln.cn

Insights

Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions achieved high success rates (90.2%) and favorable outcomes in experienced centers. Factors like occlusion time and lesion length influenced success, with low major adverse cardiac events.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Research
  • Vascular Medicine

Context:

  • Chronic total occlusion (CTO) represents a significant challenge in percutaneous coronary intervention (PCI).
  • Successful revascularization of CTO lesions can improve myocardial perfusion and patient outcomes.
  • Limited data exists on the long-term outcomes and technical success rates of CTO PCI in large patient cohorts.

Purpose:

  • To evaluate the technical success and clinical outcomes of PCI for patients with CTO lesions.
  • To identify factors affecting PCI success in CTO lesions.
  • To assess the safety and efficacy of CTO PCI procedures.

Summary:

  • A retrospective analysis of 1148 patients with 1494 CTO lesions treated with PCI between 1993-2004.
  • Overall success rates were 90.2% for patients and 88.2% for lesions.
  • Success was lower for longer occlusions, stump issues, bridging collaterals, and lesions >= 15mm. In-hospital major adverse cardiac events were 0.6%.

Impact:

  • Demonstrates that high success rates and favorable clinical outcomes are achievable with PCI for CTO lesions in experienced centers.
  • Provides insights into factors influencing CTO PCI success, aiding procedural planning.
  • Contributes to the understanding of the safety profile of CTO PCI, with low rates of major adverse cardiac events.
Abstract

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