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Patellamide E: a new cyclic peptide from the ascidian Lissoclinum patella
1Department of Medicinal Chemistry, University of Utah, Salt Lake City 84112.
Journal of Natural Products
|March 1, 1992
Abstract:
A new cyclic peptide, patellamide E [1], was isolated from the ascidian Lissoclinum patella collected at Pulau Salu, Singapore. Its structure was determined by nmr spectroscopy, and its absolute configuration by acid hydrolysis and analysis of the derivatized constituent amino acids by hplc. Patellamide E was mildly cytotoxic against human colon tumor cells in vitro.