Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparison of diagnostic findings using different olfactory test methods.

Toshiaki Tsukatani1, Evan R Reiter, Takaki Miwa

  • 1Department of Otolaryngology-Head and Neck Surgery, VA Commonwealth University, Richmond, Virginia 23298, USA.

The Laryngoscope
|June 4, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Successful Multimodal Treatment of SMARCA4-Deficient Sinonasal Carcinoma.

Ear, nose, & throat journal·2026
Same author

JAG1 expression in papillary thyroid cancer stem-like cells predicts poor prognosis and implicates angiogenesis.

Discover oncology·2026
Same author

Summary of Japanese clinical practice guidelines 2025 for the management of olfactory dysfunction.

Auris, nasus, larynx·2026
Same author

Olfactory Implants to Restore Smell: Where to Stimulate?

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2026
Same author

Effects of Toki Shakuyaku San on Olfactory Function in a Postmenopausal Mouse Model.

Cureus·2025
Same author

Olfactory deprivation promotes amyloid β deposition in a mouse model of Alzheimer's disease.

Brain research·2025

Comparing olfactory testing methods reveals significant discrepancies in diagnosing hyposmia. While anosmia and normosmia diagnoses align well, different olfactory tests yield varied results for mild, moderate, and severe hyposmia.

Area of Science:

  • Olfactory research
  • Sensory science
  • Clinical diagnostics

Background:

  • Olfactory function assessment is crucial for diagnosing various neurological and sinonasal conditions.
  • Standardization of olfactory testing methods is lacking, leading to potential discrepancies in clinical and research data.
  • The Connecticut Chemosensory Clinical Research Center (CCCRC) test and the Jet Stream Olfactometer (JSO) test are widely used but differ in methodology.

Purpose of the Study:

  • To quantify diagnostic discrepancies in olfactory function between two distinct testing methods: the CCCRC test and the JSO test.
  • To assess the reliability of comparing olfactory test results across different centers and methodologies.
  • To identify specific olfactory function categories where diagnostic agreement is highest and lowest.

Main Methods:

Related Experiment Videos

  • A prospective study involving 50 healthy volunteers and 25 patients with olfactory complaints.
  • Olfactory function was assessed in each nostril using both the CCCRC test (US) and the JSO test (Japan).
  • Participants were categorized into normosmia, mild hyposmia, moderate hyposmia, severe hyposmia, or anosmia based on test results.

Main Results:

  • A significant correlation (rs = 0.788, P < .01) was observed between the CCCRC and JSO test methods.
  • Diagnostic categories matched in 66.7% of tested nostrils; results differed by more than one category in only 7.3%.
  • High agreement (91.7%) was found for anosmia and normosmia, but agreement dropped significantly (22.2%) for hyposmic categories (mild, moderate, severe).

Conclusions:

  • Comparing clinical or research data requires careful consideration of the olfactory testing methods used.
  • Diagnoses of anosmia and normosmia appear more reliably comparable between different olfactory test methods.
  • Significant variability exists when comparing hyposmia diagnoses obtained using different olfactory testing methodologies, necessitating method-specific data interpretation.