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Development of a shape memory alloy multiple-point injector for chemotherapy.
1Centre for Biomedical Engineering, School of Engineering, University of Surrey, Guildford, UK. w.xu@surrey.ac.uk
Summary
This study introduces a novel medical needle capable of multi-site injections via a single puncture. Finite element modeling of shape memory alloy needles predicted and confirmed penetration forces for improved medical treatments like liver cancer therapy.
Area of Science:
- Biomedical Engineering
- Materials Science
- Medical Devices
Background:
- Minimally invasive procedures are crucial in modern medicine.
- Current injection techniques may require multiple punctures, increasing patient discomfort and risk.
- Targeted therapies, such as for liver cancer, demand precise and efficient drug delivery.
Purpose of the Study:
- To develop and model a novel multi-site injection needle.
- To investigate the mechanical properties of shape memory alloy (SMA) inner needles.
- To validate the finite element model with experimental data.
Main Methods:
- Design and fabrication of a medical needle with multiple, extrudable internal needles.
- Development of a finite element model using non-linear elastic elements to simulate SMA behavior.
- Experimental measurement of needle tip deformation force versus displacement.
Main Results:
- The finite element model accurately predicted maximum strain and penetration forces for the SMA inner needles.
- Experimental validation confirmed the model's predicted penetration forces.
- The developed needle design enables multi-site injections through a single stab wound.
Conclusions:
- The novel multi-site injection needle, utilizing SMA inner needles, is a viable innovation.
- Finite element modeling is an effective tool for predicting the performance of such medical devices.
- This technology has significant potential applications, including minimally invasive liver cancer treatment.