[Preoperative evaluation and management of patients with ischemic heart disease undergoing noncardiac surgery]
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1Department of Cardiovascular Surgery, Fukushima Medical University, Fukushima, Japan.
Insights
Managing coronary artery disease (CAD) in patients needing noncardiac surgery is crucial. Off-pump coronary artery bypass (OPCAB) offers a safe revascularization option, potentially performed alongside other surgeries.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Anesthesiology
Context:
- Increasing prevalence of coronary artery disease (CAD) in aging populations presents challenges for noncardiac surgery.
- Current management of CAD includes medical therapy, percutaneous coronary intervention (PCI) with stents, and coronary artery bypass grafting.
- Drug-eluting stents (DES) pose risks of late stent thrombosis if antiplatelet therapy is discontinued before noncardiac surgery.
Purpose:
- To evaluate management strategies for patients with CAD undergoing noncardiac surgery.
- To explore the role of off-pump coronary artery bypass (OPCAB) in this patient population.
Summary:
- Off-pump coronary artery bypass (OPCAB) is a safe and effective revascularization technique that avoids cardiopulmonary bypass.
- OPCAB can be performed simultaneously or staged with noncardiac procedures like carotid endarterectomy or aortic aneurysm resection.
- This approach mitigates risks associated with prolonged antiplatelet therapy after PCI, particularly with drug-eluting stents.
Impact:
- OPCAB presents a viable and promising option for patients with both CAD and noncardiac disease requiring surgical intervention.
- Improved management strategies can reduce perioperative cardiac events and optimize surgical outcomes.
- This facilitates timely noncardiac procedures for patients with complex cardiovascular conditions.
Abstract:
The evaluation and management of patients with coronary artery disease (CAD) undergoing noncardiac surgery are becoming important medical issues in modern society with the aging of the population and prevalence of CAD. For patients with CAD, medical therapy (beta-blockers, statins), percutaneous coronary artery intervention (PCI) with/without stenting, and coronary artery bypass grafting have been the modalities for management. Although balloon angioplasty is effective in selected patients, bare-metal stents (BMS) require post-PCI antiplatelet therapy for 4-6 weeks delaying noncardiac procedures As recently reported patients with drug-eluting stents (DES) experienced late stentthrombosis due to discontinuation of antiplatelet therapy in the long-term period before noncardiac surgery, suggesting the need for life-long anticoagulant therapy after DES placement. Recently, offpump coronary artery bypass (OPCAB) has become a safe and effective procedure for direct coronary revascularization. OPCAB, without cardiopulmonary bypass and its adverse effects, can be performed simultaneously with noncardiac surgery such as carotid endoarterectomy, abdominal aortic aneurysm resection, and peripheral arterial reconstruction. OPCAB is a promising option as a simultaneous or staged procedure for patients with CAD and noncardiac disease.
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