Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lactobacillus surface layers and their applications.

Silja Avall-Jääskeläinen1, Airi Palva

  • 1Department of Basic Veterinary Sciences, Division of Microbiology and Epidemiology, University of Helsinki, P.O. Box 66, Agnes Sjoberginkatu 4, FIN-00014, Finland.

FEMS Microbiology Reviews
|June 7, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Learning Outcomes of Interactive Online Cases in Veterinary Epidemiology and Bacteriology Education: A Survey Study.

Advances in medical education and practice·2025
Same author

Emergence of Capnocytophaga canimorsus and Capnocytophaga cynodegmi in oral cavities of newborn puppies, a pilot study.

Acta veterinaria Scandinavica·2024
Same author

The crystal structure of the N-terminal domain of the backbone pilin LrpA reveals a new closure-and-twist motion for assembling dynamic pili in Ligilactobacillus ruminis.

Acta crystallographica. Section D, Structural biology·2024
Same author

The molecular architecture of <i>Lactobacillus</i> S-layer: Assembly and attachment to teichoic acids.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Redesigning and teaching veterinary microbiology laboratory exercises with combined on-site and online participation during the COVID-19 pandemic.

FEMS microbiology letters·2021
Same author

LrpCBA pilus proteins of gut-dwelling Ligilactobacillus ruminis: crystallization and X-ray diffraction analysis.

Acta crystallographica. Section F, Structural biology communications·2021
Same journal

Feeding the invaders: How metabolic imbalance shapes infection and biofilm development.

FEMS microbiology reviews·2026
Same journal

Interactions between extracellular vesicles and viruses: lessons learned across species and kingdoms.

FEMS microbiology reviews·2026
Same journal

Killer Peptide: an antibody-derived self-assembling peptide bridging antimicrobial and host-defense mechanisms.

FEMS microbiology reviews·2026
Same journal

From gatekeeper to target: MAPK cascades as control circuits at the insect-microbe interface.

FEMS microbiology reviews·2026
Same journal

The role of fungal G protein-coupled receptors in interspecies cell-cell communication.

FEMS microbiology reviews·2026
Same journal

Convergent symbioses: morphology, life history, and niche specialization in coral and lichen mutualisms.

FEMS microbiology reviews·2026
See all related articles

Lactobacillus surface (S-) layer proteins, though sharing amino acid similarities, exhibit low sequence similarity and unique characteristics. These proteins are crucial for host tissue adhesion and have potential applications as antigen delivery vehicles.

Area of Science:

  • Microbiology
  • Bacterial Cell Walls
  • Protein Structure

Background:

  • Surface (S-) layers are crystalline protein arrays forming the outermost cell wall component in many bacteria and Archaea, including Lactobacillus species.
  • Lactobacillus S-layer proteins are typically small with high predicted isoelectric points (pI), distinguishing them from other S-layer proteins despite amino acid compositional similarities.
  • Some Lactobacillus species possess multiple S-layer protein genes that can be expressed individually or concurrently.

Purpose of the Study:

  • To summarize the characteristics of Lactobacillus S-layer proteins.
  • To highlight their known functions, particularly in host tissue adhesion.
  • To outline existing and potential applications of these proteins.

Main Methods:

Related Experiment Videos

  • Literature review of S-layer proteins in Lactobacillus species.
  • Analysis of reported amino acid composition, sequence similarity, size, and pI values.
  • Compilation of characterized functions and existing applications.

    • Main Results:

    • Lactobacillus S-layer proteins show low overall sequence similarity despite conserved amino acid composition.
    • Key distinguishing features include small size and high predicted pI values.
    • Functions primarily involve mediating adhesion to host tissues.

    Conclusions:

    • Lactobacillus S-layer proteins are structurally diverse yet functionally significant for bacterial-host interactions.
    • Their unique properties make them promising candidates for biotechnological applications, such as antigen delivery vehicles.