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Updated: Dec 24, 2025

Reconstitution of Septin Assembly at Membranes to Study Biophysical Properties and Functions
Published on: July 28, 2022
The membrane-water interface region of membrane proteins: structural bias and the anti-snorkeling effect
Jie Liang1, Larisa Adamian, Ronald Jackups
1Department of Bioengineering, University of Illinois at Chicago, M/C563, 835 S. Wolcott Avenue, Chicago, IL 60612-7340, USA. jliang@uic.edu
Abstract:
Membrane proteins have important roles in many cellular processes. Computational analysis of their sequences and structures has provided much insight into the organizing principles of transmembrane helices. In a recent study, the membrane-water interface region was examined in detail for the first time. The results have revealed that this interface region has an important role in constraining protein secondary structure. This study raises new questions and opens up new directions for studying membrane proteins.
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