Related Experiment Video
Updated: Aug 17, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
Published on: May 12, 2023
Particulate delivery systems for biodefense subunit vaccines
Vincent W Bramwell1, Jim E Eyles, H Oya Alpar
1School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Abstract:
Expanding identification of potentially protective subunit antigens and correlates of protection has provided a basis for the introduction of safer vaccines. Despite encouraging results in animal models, the significant potential of particulate delivery systems in vaccine design has not yet translated into effective vaccines available for use in humans. This review article will focus on the current status of the development of particulate vaccines, mainly liposomes and bio-degradable polymers, against potential agents for biowarfare: plague, anthrax, botulinum, and smallpox; and filoviruses: Marburg and Ebola.
Related Concept Videos
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Vaccines
Vaccine Production
Vaccinations
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Smallpox

