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Naproxen induced ulcerative esophagitis.

G A Ecker1, J Karsh

  • 1Division of Rheumatology, Ottawa General Hospital, University of Ottawa, Ontario, Canada.

The Journal of Rheumatology
|April 1, 1992
PubMed
Summary
This summary is machine-generated.

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Nonsteroidal anti-inflammatory drug (NSAID) use can cause ulcerative esophagitis, a rare cause of upper gastrointestinal bleeding in the elderly. This case highlights the importance of considering NSAIDs in older patients with esophageal issues.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Geriatrics

Background:

  • Upper gastrointestinal bleeding (UGIB) is a common emergency in the elderly.
  • Ulcerative esophagitis accounts for only 4% of UGIB cases in this population.
  • Nonsteroidal anti-inflammatory drug (NSAID)-related esophageal bleeding is infrequently reported.

Observation:

  • A case of an 87-year-old woman presenting with symptoms of upper gastrointestinal bleeding.
  • The patient had a history of documented esophageal dysmotility.
  • Esophageal ulceration was identified as the source of bleeding.

Findings:

  • The ulcerative esophagitis was determined to be induced by nonsteroidal anti-inflammatory drug (NSAID) use.
  • This represents a rare instance of NSAID-induced esophageal bleeding.

Related Experiment Videos

  • Esophageal dysmotility may have contributed to the development of NSAID-induced ulcerative esophagitis.

    • Implications:

    • Clinicians should consider NSAID-induced ulcerative esophagitis in elderly patients with UGIB, especially those with pre-existing esophageal motility disorders.
    • NSAID use should be carefully evaluated in older adults presenting with esophageal symptoms or bleeding.
    • This case underscores the potential gastrointestinal toxicity of NSAIDs in a vulnerable elderly population.