Related Experiment Video
Updated: Aug 17, 2026

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
Published on: March 17, 2012
Rapid progression of amyotrophic lateral sclerosis presenting during pregnancy: a case report
David E Leveck1, Gregory A Davies
1Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Queen's University, Kingston ON.
Background:
Amyotrophic lateral sclerosis (ALS) is a progressive neurologic disease that is rare within the obstetric population. Only 5 reports of ALS in pregnancy have appeared in the medical literature since 1977.
Case:
A previously healthy 25-year-old pregnant woman with 2 previous births presented with generalized weakness at 22 weeks' gestation. Initial laboratory values were all normal. She was admitted to hospital at 29 weeks' gestation and intubated because of respiratory compromise. Daily biophysical profiles and amniotic fluid indices were normal. Labour was induced at 34.5 weeks' gestation, and delivery was uncomplicated. She died at 9 months postpartum.
Conclusion:
Pregnancy complicated by the onset of ALS is a rare event. Complications of this disease mainly affect the respiratory system. Death in this case occurred more rapidly than in other previously reported cases.
More Related Videos
Related Concept Videos
Multiple Sclerosis l: Introduction
Parkinson's Disease: Overview
Parkinson Disease l: Introduction
Alzheimer Disease l: Introduction
Cross-bridge Cycle
Parkinson Disease ll: Pathophysiology

