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Pertussis with severe pulmonary hypertension and leukocytosis treated with extracorporeal membrane oxygenation

Brittany B De Berry1, James E Lynch, Dai H Chung

  • 1Department of Surgery, The University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

Pediatric Surgery International
|June 7, 2005
PubMed

Insights

Severe pertussis infection in an infant was successfully treated with extracorporeal membrane oxygenation (ECMO). This case highlights ECMO

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Pertussis, caused by Bordetella pertussis, is a significant global cause of infectious disease mortality.
  • Infants, particularly those under one year of age, are at high risk for severe pertussis complications.

Observation:

  • A 5-week-old infant girl presented with severe pertussis, extreme leukocytosis, and respiratory failure.
  • The infant required prolonged extracorporeal membrane oxygenation (ECMO) for life support.

Findings:

  • Nitric oxide therapy effectively resolved pulmonary hypertension in the infant.
  • The infant was successfully weaned from ECMO and discharged after 3 months of intensive care.

Implications:

  • Extracorporeal membrane oxygenation (ECMO) can be a life-saving intervention for severe pertussis-induced respiratory failure in infants.
  • This case underscores the critical role of extracorporeal life support in managing severe pediatric infectious diseases with poor prognostic indicators.

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