Chemical library synthesis using convergent approaches
Aaron B Beeler1, Scott E Schaus, John A Porco
1Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
Current Opinion in Chemical Biology
|June 9, 2005
Abstract:
New strategies are continuously being developed in combinatorial and diversity-oriented synthesis. Convergent design in target-oriented synthesis is commonly employed for construction of complex molecules. In this mini-review, we describe examples of convergent library design and synthesis as well as potential areas for future development.


