Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical effectiveness of processed and unprocessed bone.

G Galea1, J N Kearney

  • 1Tissue Services, Scottish National Blood Transfusion Service, Edinburgh, UK. george.galea@snbts.csa.scot.nhs.uk

Transfusion Medicine (Oxford, England)
|June 10, 2005
PubMed
Summary

Bone allografts are effective but require better understanding of bone healing and banking processes. Improving safety and effectiveness necessitates understanding provider and user needs for banked bone quality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimisation of non-contrast CT examinations using tin (Sn) filtration: A systematic review.

Radiography (London, England : 1995)·2025
Same author

Comparison of bone marrow component removal from processed femoral head bone from living and deceased donors: presence of geodes in living donor bone can prevent maximum removal of marrow components.

Cell and tissue banking·2018
Same author

Assessment of the permeability properties of cryopreservation outer bags used in NHSBT.

Cell and tissue banking·2018
Same author

In vitro biomechanical and hydrodynamic characterisation of decellularised human pulmonary and aortic roots.

Journal of the mechanical behavior of biomedical materials·2017
Same author

Development and characterisation of a large diameter decellularised vascular allograft.

Cell and tissue banking·2017
Same author

Assessment of a closed wash system developed for processing living donor femoral heads.

Cell and tissue banking·2017

Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Tissue Engineering

Background:

  • Bone allografts have a long history of clinical use in various surgical procedures.
  • While clinically effective, evidence supporting bone allografts often comes from retrospective, non-randomized studies.
  • Bone banking practices aim to enhance the quality and safety of allografts for surgical applications.

Purpose of the Study:

  • To review current data on bone allografts and bone banking.
  • To highlight challenges in evaluating the effectiveness and safety of banked bone.
  • To emphasize the need for better understanding of provider and user requirements.

Main Methods:

  • Literature review summarizing existing data on bone allografts and banking.
  • Analysis of clinical effectiveness and safety considerations.

Related Experiment Videos

  • Identification of challenges in research and development.

    • Main Results:

    • Bone allografts are clinically effective, but robust evidence is limited.
    • Bone banking processes are increasingly controlled, focusing on safety and efficacy.
    • Difficulties exist in standardizing research and demonstrating clear benefits.

    Conclusions:

    • Further research is needed to improve bone allograft quality and safety.
    • Understanding the needs of both bone allograft providers and surgical users is crucial.
    • Optimizing banked bone effectiveness requires a balanced approach to safety and biological performance.