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Multicomponent collection as of 2005.

M Valbonesi1, G Giannini, F Morelli

  • 1Department of Immunohematology, San Martino University Hospital, Largo Rosanna Benzi 10, 16132 Genova, Italy. mauro.valbonesi@hsanmartino.it

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|June 10, 2005
PubMed
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Multicomponent apheresis (MCA) offers cost savings and improved safety by collecting multiple blood components from a single donor. This technique, including platelet and red blood cell collection, enhances transfusion safety and donor acceptance.

Area of Science:

  • Transfusion Medicine
  • Blood Component Collection

Background:

  • Multicomponent apheresis (MCA) originated in Genoa in 1985 as autologous "sequestration" for preoperative component collection.
  • Initial application in 1986 focused on donor platelet apheresis to reduce costs and viral transmission risks.

Purpose of the Study:

  • To evaluate the evolution and benefits of multicomponent apheresis (MCA).
  • To highlight MCA's role in cost reduction and enhanced patient safety in blood transfusion.

Main Methods:

  • Development of "aggressive MCA" to collect 2 units of platelets and 1-2 units of PRBCs from selected donors.
  • Implementation of "dry-platelet collection" with resuspension in solutions like T-Sol.
  • Advancement to independent RBC apheresis collection.

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Main Results:

  • MCA enables concurrent collection of platelets, plasma, and PRBCs, maximizing yield.
  • Dry-platelet collection and T-Sol resuspension improved efficiency.
  • MCA has demonstrated significant cost-saving capabilities and increased patient safety over 15 years.
  • High donor acceptance rates since 1989 for concurrent component collection.

Conclusions:

  • MCA represents a significant advancement in blood collection, moving towards apheresis as the sole method.
  • The technique offers substantial cost savings and improved safety for transfusion recipients.
  • MCA has achieved widespread acceptance due to its efficiency and donor compatibility.