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Updated: Aug 17, 2026

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat
Published on: July 26, 2015
[Functional renal reserve and glomerular hyperfiltration]
1Dipartimento di Medicina Interna, Università degli Studi di Pisa, Pisa, Italy. m.camici@med.unipi.it
Abstract:
The hemodynamic theory of progressive renal disease with glomerular hyperfiltration has been proposed as common final pathway of kidney disease progression. The evaluation of renal functional reserve is an useful approach to point out glomerular hyperfiltration. First the author describes the meaning of renal functional reserve, mechanisms of glomerular hemodynamic regulation and renal reaction to proteic load and finally explains the practical application of renal functional reserve in clinical nephrology.
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