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Proliferative pododermatitis (canker) with intralesional spirochetes in three horses
Claude M Nagamine1, Fernando Castro, Ben Buchanan
1University of Tennessee College of Veterinary Medicine, Knoxville, TN 37996-4542, USA.
Summary
Spirochetes were found in the foot lesions of horses with canker, a chronic foot disease. This suggests spirochetes may play a role in equine foot conditions, similar to their role in cattle and sheep.
Area of Science:
- Veterinary Pathology
- Microbiology
- Equine Medicine
Background:
- Chronic foot diseases in horses, such as canker (proliferative pododermatitis), pose significant challenges in equine veterinary medicine.
- The etiology of many chronic equine foot conditions remains incompletely understood, necessitating further investigation into potential causative agents.
Observation:
- Histological examination of tissue samples from three horses diagnosed with canker revealed the presence of spirochetes.
- These spirochetes were identified within the proliferative lesions characteristic of the disease.
Findings:
- The histological evidence strongly suggests a correlation between spirochete identification and the presence of canker in horses.
- The findings indicate that spirochetes may be a contributing factor to the pathological processes observed in equine canker.
Implications:
- These findings imply that spirochetes could be a significant etiological agent in equine chronic foot diseases.
- Further research into spirochetal infections in horses may lead to improved diagnostic and therapeutic strategies for conditions like canker.
- The comparison to bovine papillomatous digital dermatitis and contagious ovine digital dermatitis suggests a potential commonality in the pathogenesis of digital diseases across species, driven by spirochetes.

