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Updated: Aug 17, 2026
One-anastomosis Gastric Bypass (OAGB) in Rats
Published on: November 10, 2018
Laparoscopic gastric bypass with silicone band in a pig model: prevention of anastomotic dilatation -- feasibility
David Nocca1, Michel Gagner, Federico Cuenca Abente
1Minimally Invasive Surgery Center, Mount Sinai Hospital, New York, USA. d.nocca@wanadoo.fr
Background:
Morbid obesity has become a major global health problem. Surgery remains the only effective treatment for patients with severe obesity, because diet reduction methods and pharmacologic agents have not resulted in long-term weight reduction. Gastric bypass (GBP) can provide adequate weight loss, but after some years, dilatation of the gastric pouch and outlet may lead to weight regain by allowing the patient to increase food intake.
Methods:
2 groups of 6 pigs underwent laparoscopic GBP. In the first group, a non-adjustable silicone band (Proring-band, IOC, Innovative Obesity Care, Saint Etienne, France) was positioned 1 cm proximal to the gastrojejunal anastomosis. In the second group, the device used to stabilize the gastric pouch was an adjustable silicone band (Mid-band, Medical Innovation Developpement, Villeurbanne, France). Weight loss, complications and histological reaction were evaluated after 3 months.
Results:
Mortality rate was 25% (cardiac arrythmia in 2 pigs). Conversion rate was 25%. The positioning of the band was more difficult with the Mid-band because of its larger size and the presence of the catheter. The average weight change in the Proring group was 15.8 kg (3.5-25.1 kg), and in the Mid-band group was 12.0 kg (6.2-15.1 kg). Morbidity consisted of one intragastric migration of the Proring band into the gastrojejunal anastomosis, and one infection of the port in the Mid-band group treated by removal of the port and antibiotics.
Conclusion:
Use of silicone devices may be safe and effective in the prevention of pouch or outlet dilatation after GBP.
