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[Surgical management for pulmonary metastasis]
Yi Zhang1, Jia-an Ding, Bo-xiong Xie
1Department of Thoracic Surgery, Shanghai Pulmonary Disease Hospital, Shanghai 200433, China. yeechang120@yahoo.com.cn
Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|June 11, 2005
Summary
Surgical resection of lung metastasis offers significant survival benefits for select patients. Key indicators for longer survival include solitary lesions and a disease-free interval greater than 36 months.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Context:
- Lung metastasis presents a significant challenge in cancer management.
- Surgical intervention is a potential treatment modality for selected patients with pulmonary metastases.
- Long-term outcomes and prognostic factors require continuous investigation.
Purpose:
- To evaluate the indications, surgical procedures, and survival outcomes of lung metastasis resection.
- To identify prognostic factors influencing survival after pulmonary metastasis surgery.
- To refine surgical strategies for patients with lung metastases.
Summary:
- This study analyzed 108 patients undergoing surgery for lung metastasis (93% carcinoma, 17% sarcoma).
- Procedures included partial resection, lobectomy, and pneumonectomy.
- Survival rates at 1, 3, 5, 7, and 10 years were 87.9%, 47.3%, 31.7%, 23.7%, and 13.9%, respectively, with a median survival of 34.8 months.
- Solitary lesions, disease-free interval >36 months, absence of extrathoracic disease, and open thoracotomy predicted longer survival.
- Age, gender, symptoms, and primary tumor pathology were not significant prognostic factors.
Impact:
- Identifies critical criteria for patient selection in lung metastasis resection.
- Highlights 'open' thoracotomy as a potentially superior surgical approach.
- Guides clinical decision-making for surgical treatment of pulmonary metastases.
- Emphasizes cautious consideration for patients with short disease-free intervals or multiple lesions.