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Updated: Jul 30, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[The scientific information that the pharmaceutical industry provides to family doctors]
F Rivera Casares1, M J Richart Rufino, J Navas Cutanda
1CS Fuensanta, Valencia, Spain. frivera@comv.es
Objective:
To check whether the information in the written publicity that the pharmaceutical industry gives to family doctors really is based on the scientific studies that support it.
Design:
Cross-sectional study.
Setting:
Health centre on the outskirts of a big city.
Participants:
Over a year, all the scientific studies that laboratory reps gave family doctors along with the advertising for medicines were collected. A total of 63 paired studies and advertising pieces were obtained.
Main Measurements:
1-3 advertising messages with each supporting study were selected and reviewed in a structured fashion. Then whether or not the messages selected were based on the study was appraised.
Results:
44.5% of the advertising messages were not based on the accompanying study; 29.9% clearly were based on the study; and in the rest there was a half-and-half relationship. There was a significant relationship between the evaluation of the advertising messages and the kind of study, masking and the kind of result variable.
Conclusions:
A high proportion of advertising messages are not based on the study that is reputed to support them. A critique of these studies has to be undertaken before the advertising messages can be looked at.
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