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Chromatin Immunoprecipitation from Dorsal Root Ganglia Tissue following Axonal Injury
Published on: July 20, 2011
Spinal cord ganglioglioma presenting as acute paraparesis
Graham Joseph Jeffs1, Gabriel Yin Foo Lee, George Tse-Hwai Wong
1Department of Neurosurgery, Sir Charles Gairdner Hospital, Perth, WA, Australia. jeffsyg@hotmail.com
Abstract:
A 17-year-old male presented with acute onset paraparesis in the lower limbs. Urinary retention was present and the patient required catheterisation. Clinical examination confirmed severe bilateral lower limb weakness and a sensory level at T8. Magnetic resonance imaging (MRI) revealed a haemorrhagic intramedullary tumour extending from T8 to the conus. Microsurgical excision of the tumour was performed and the patient made a good functional recovery. The histology of the tumour demonstrated a ganglioglioma of the spinal cord. Acute paraparesis has not previously been reported with a spinal cord ganglioglioma. We discuss the clinical, diagnostic and pathological features of spinal cord gangliogliomas.
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