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Related Experiment Videos

DENSE with SENSE.

Anthony H Aletras1, W Patricia Ingkanisorn, Christine Mancini

  • 1Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA. AletrasA@nhlbi.nih.gov

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|June 11, 2005
PubMed
Summary

This study introduces a faster cardiac imaging technique combining Displacement Encoding with Stimulated Echoes (DENSE) and SENSE acceleration. This method halves breath-hold times for myocardial contractility studies while maintaining excellent strain map quality.

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Area of Science:

  • Cardiovascular Magnetic Resonance Imaging
  • Biomedical Engineering
  • Medical Physics

Background:

  • Assessing regional myocardial contractility is crucial for diagnosing cardiac conditions.
  • Traditional cardiac MRI techniques often require prolonged breath-holds, limiting patient comfort and data acquisition.
  • Accelerated imaging methods are needed to improve efficiency and patient experience in cardiac MRI.

Purpose of the Study:

  • To describe and evaluate a novel accelerated DENSE MRI technique for cardiac imaging.
  • To reduce total breath-hold time during myocardial contractility studies.
  • To maintain high-quality strain mapping despite accelerated acquisition.

Main Methods:

  • Implementation of a low encoding strength phase-cycled meta-DENSE readout.

Related Experiment Videos

  • Integration with a two-fold SENSE acceleration (R = 2).
  • Acquisition and analysis of data from phantoms, healthy volunteers, and a patient.

    • Main Results:

    • The combined SENSE-DENSE technique successfully reduced total breath-hold time by 50%.
    • Strain map quality was preserved, demonstrating the efficacy of the accelerated method.
    • Feasibility was shown across phantom, volunteer, and patient datasets.

    Conclusions:

    • The SENSE-accelerated DENSE sequence offers a significant reduction in scan time for cardiac imaging.
    • This technique enhances patient comfort without compromising the diagnostic quality of myocardial strain analysis.
    • This approach holds promise for routine clinical application in cardiac assessment.