Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development and validation of a survey-based COPD severity score.

Mark D Eisner1, Laura Trupin, Patricia P Katz

  • 1Department of Medicine, University of California, San Francisco, 350 Parnassus Ave, Ste 609, San Francisco, CA 94117, USA. eisner@itsa.ucsf.edu

Chest
|June 11, 2005
PubMed
Summary

A new COPD severity score reliably measures disease impact in adults, correlating with poorer lung function and quality of life. This tool aids epidemiologic research without needing pulmonary function tests.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recreational drug inhalation and socioenvironmental determinants of pulmonary infection in patients with HIV: a hospital-based case control study.

BMC public health·2026
Same author

Toxic skies of war.

The Lancet. Respiratory medicine·2026
Same author

Implications of year 1 Trump Administration policies for Americans' lung health.

American journal of respiratory and critical care medicine·2026
Same author

Characterizing the relationship between air pollution and childhood cognition in the Children's health and air pollution study.

Environmental research·2026
Same author

<i>Coccidioides</i> skin test performance and patterns of prior immunity to coccidioidomycosis among a large population of males entering California state prisons, 2015-2024: a population-based modelling study.

Lancet regional health. Americas·2026
Same author

Climate change and allergic diseases: A scoping review.

The journal of climate change and health·2026

Area of Science:

  • Pulmonary Medicine
  • Epidemiology
  • Health Outcomes Research

Background:

  • Chronic Obstructive Pulmonary Disease (COPD) poses a significant public health challenge.
  • Accurate assessment of COPD severity is crucial for epidemiologic research and clinical management.
  • Existing instruments may not fully capture the multifaceted nature of COPD severity for survey-based studies.

Purpose of the Study:

  • To develop and validate a comprehensive, disease-specific instrument to measure COPD severity.
  • To create a tool suitable for large-scale, survey-based epidemiologic research.
  • To establish a COPD severity score that is reliable and valid.

Main Methods:

  • A population-based sample of 383 US adults with physician-diagnosed COPD was utilized.

Related Experiment Videos

  • A structured telephone interview assessed five key aspects of COPD severity: symptoms, medication use, hospitalizations, intubations, and home oxygen use.
  • Concurrent validity was assessed against pulmonary function (FEV1, PEFR), health-related quality of life (HRQL), and physical disability measures.

    • Main Results:

    • The developed COPD severity score demonstrated high internal consistency reliability (Cronbach alpha = 0.80).
    • Higher scores correlated significantly with poorer pulmonary function (FEV1, PEFR), reduced physical HRQL, and increased activity limitations.
    • The score was associated with a higher risk of difficulty with daily activities and inability to work.

    Conclusions:

    • The COPD severity score is a reliable and valid instrument for assessing COPD severity in research settings.
    • This validated score can be effectively used as a study outcome or for adjusting analyses in epidemiologic research.
    • The instrument's utility is enhanced as it does not necessitate pulmonary function measurements.