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Updated: Aug 17, 2026
Identification of Mycobacterium Species by DNA Microarray Chip Method
Published on: June 24, 2025
Discordant molecular characterization results in a Mycobacterium avium complex strain isolated from an AIDS patient
Tsi-Shu Huang1, Susan Shin-Jung Lee1, Yao-Shen Chen1
1Section of Microbiology and Infectious Diseases, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Rd, Kaohsiung, Taiwan 2Department of Medical Technology, Foo-Yin Institute of Technology, Kaohsiung County, Taiwan 3Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung County, Taiwan 4Dept of Internal Medicine, National Yang-Ming University, Taipei, Taiwan.
Abstract:
This report describes an unusual strain of Mycobacterium avium complex isolated from the sputum of an immunocompromised AIDS patient, which did not react with the MAC probe of the BDProbe Tec system, but was identified as Mycobacterium intracellulare by 16S rRNA gene sequencing. Its PCR restriction-enzyme analysis pattern was compatible with an allelic variant of M. avium. It was scotochromogenic, slow-growing and phenotypically identified as Mycobacterium scrofulaceum. Its clinical significance is not certain.
