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Passerini-glazel feminizing genitoplasty: a long-term followup study
Aldo Bocciardi1, Arianna Lesma, Francesco Montorsi
1Department of Urology, Vita-Salute University, San Raffaele Hospital, Milan, Italy.
The Journal of Urology
|June 11, 2005
Summary
Early feminizing genitoplasty using the Passerini-Glazel technique offers safe and effective surgical correction for ambiguous genitalia. While vaginal stenosis can occur, it is treatable with introitoplasty before menarche, ensuring good functional outcomes.
Area of Science:
- Pediatric Surgery
- Urology
- Endocrinology
Background:
- Ambiguous genitalia requires timely surgical intervention for optimal outcomes.
- Feminizing genitoplasty aims to create functional and aesthetically appropriate genitalia.
- The Passerini-Glazel technique is a specific approach to feminizing genitoplasty.
Purpose of the Study:
- To evaluate the long-term results of early 1-stage Passerini-Glazel feminizing genitoplasty.
- To specifically assess the outcomes of the vaginoplasty component of the procedure.
Main Methods:
- A cohort of 66 patients with ambiguous genitalia underwent 1-stage Passerini-Glazel feminizing genitoplasty.
- Long-term follow-up included clinical assessments at 1 and 2 years post-surgery, with genital assessments under anesthesia before menarche for younger patients.
Main Results:
- No major complications were reported in the first long-term follow-up.
- Vaginal introitus was well-positioned, large, and elastic in all assessed patients.
- Vaginal caliber at the suture line showed stenosis in 35% of patients, which was successfully treated with Y-V introitoplasty.
Conclusions:
- Early 1-stage Passerini-Glazel feminizing genitoplasty is safe and effective for ambiguous genitalia.
- Good cosmetic results are achieved with this technique.
- High incidence of vaginal stenosis is manageable with pre-menarche introitoplasty, suggesting good functional results.