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Kikuchi-Fujimoto disease: a case report

Antoni Hrycek1, Paweł Cieślik, Witold Szkróbka

  • 1Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, ul. Tysiaclecia 86a/34, 40-871, Katowice, Poland. genmar@ka.onet.pl

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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