Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DNA methylation and epigenotypes.

R Holliday1

  • 1RandL.Holliday@bigpond.com

Biochemistry. Biokhimiia
|June 14, 2005
PubMed
Summary
This summary is machine-generated.

Epigenetics explores how gene expression is controlled, with DNA methylation being a key mechanism. Understanding the human epigenome is crucial for cell differentiation, disease, and aging research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tooth wear time-bomb.

British dental journal·2026
Same author

Targeted periodontitis management in ACS patients.

British dental journal·2025
Same author

Misleading and worrying.

British dental journal·2023
Same author

Vaping misrepresentations.

British dental journal·2022
Same author

Waterline Disinfectants Reduce Dental Bioaerosols: A Multitracer Validation.

Journal of dental research·2022
Same author

Electronic cigarettes: an update on products, regulation, public health approaches and oral health.

Community dental health·2022
Same journal

Multidirectional Effects of SARS-CoV-2 Coronavirus Proteins on Amyloid Transformation of Alpha-Synuclein.

Biochemistry. Biokhimiia·2026
Same journal

Dependence of Antioxidant and Transcriptional Responses to Periodic Hypoxia on Sex and Age in Rats.

Biochemistry. Biokhimiia·2026
Same journal

Effect of the PPARγ Agonist Pioglitazone on Rat Behavior and Expression of Epileptogenesis-Related Genes during the Latent Phase of the Lithium-Pilocarpine Model.

Biochemistry. Biokhimiia·2026
Same journal

A Conjugate of Aminoadamantane and Tetrahydro-γ-Carboline Inhibits Accumulation of Mutant α-Synuclein A53T in the Cellular Model of Proteinopathy.

Biochemistry. Biokhimiia·2026
Same journal

Immunoinflammatory Markers in Patients with Affective Disorders: Genetic Polymorphisms, Peripheral Cytokine Levels, and Expression of IL-1β, IL-13, TNF-β, and TGF-α in Peripheral Blood Mononuclear Cells.

Biochemistry. Biokhimiia·2026
Same journal

Method for Individual Assessment of Human Cerebral Cortex Activity by a Combined Use of Magnetic Resonance Spectroscopy of Glutamate and BOLD Signal Method.

Biochemistry. Biokhimiia·2026
See all related articles

Area of Science:

  • Epigenetics: The study of mechanisms controlling gene expression and cellular phenotypes.

Background:

  • Epigenetics governs the genetic program for development and cell differentiation.
  • DNA methylation is a primary epigenetic mechanism regulating gene activity and stable phenotypes.

Purpose of the Study:

  • To outline the scope and future directions of epigenetics research.
  • To highlight the significance of DNA methylation patterns in various biological contexts.

Main Methods:

  • The Human Epigenome Project aims to map DNA methylation patterns across diverse cell types.
  • Investigating epigenetic reprogramming during gametogenesis and early development.

Main Results:

  • DNA methylation patterns vary between cell types, especially for specialized genes.

Related Experiment Videos

  • Common methylation sites exist, particularly in repetitive genetic elements.

    • Conclusions:

    • Epigenetic mechanisms, particularly DNA methylation, are fundamental to cellular identity and function.
    • Further research is needed to understand epigenetic defects in aging and familial diseases, building on knowledge of cancer epigenetics.