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The D box asserts itself
Thomas J Owens1, M Andrew Hoyt
1Department of Biology, The Johns Hopkins University, Baltimore, Maryland 21218, USA.
Abstract:
New findings (Burton et al., 2005; Kraft et al., 2005) demonstrate the direct recognition of D and KEN boxes, short sequence elements in substrates of the anaphase-promoting complex/cyclosome (APC/C), by APC/C coactivators and indicate a special role for the D box in the assembly of catalytically active APC/C.
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