[Primary adenocarcinoma of the appendix]

Area of Science:

• Gastroenterology
• Surgical Oncology

Background:

• Primary adenocarcinoma of the appendix is a rare malignancy.
• Its incidence and clinical presentation are infrequently documented.

Observation:

• The study analyzed 24 cases of primary appendiceal adenocarcinoma over a ten-year period.
• Common presentation mimics acute appendicitis, with other symptoms including melaena and organ infiltration in rare instances.
• Diagnosis during appendectomy is infrequent.

Findings:

• Colonic-type adenocarcinoma is most common, exhibiting rapid local spread.
• Right-sided hemicolectomy is the preferred surgical approach for advanced disease.
• Simple appendectomy may suffice for early-stage (Dukes A) mucinous adenocarcinoma.
• Palliative surgery is an option for advanced stages.

Implications:

• Early diagnosis and appropriate surgical management are crucial for appendiceal adenocarcinoma.
• Treatment strategies and prognosis parallel those of adenocarcinoma of the colon.
• Radiotherapy and chemotherapy warrant consideration based on disease stage and patient condition.