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Updated: Aug 17, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Primary signet ring cell carcinoma of urinary bladder. A case report]
S Krichen Makni1, S Ellouz, A Khabir
1Laboratoire d'anatomie et de cytologie pathologique, CHU Habib-Bourguiba, 3029 Sfax, Tunisie. akabdelmajid@yahoo.fr
Abstract:
Primary signet ring cell carcinoma of urinary bladder is a rare tumor; accounting for approximately 0.24% of all bladder malignancies. In this study, we report a case of a 58-year old man who consulted for complaints of gross hematuria, the bladder biopsy showed signet ring cell carcinoma; the exploration of gastrointestinal tract did not reveal any other tumor localizations. A total cystoprostatectomy was performed followed by radiotherapy. The aim of this study is to determine the anatomoclinical, therapy and evolution characteristics of this rare tumor.
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