Related Experiment Video
Updated: Aug 17, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Evaluation of depressive symptoms and sleep alterations in college students
Jesús Moo-Estrella1, Hugo Pérez-Benítez, Francisco Solís-Rodríguez
1Department of Neurosciences, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
Background:
Increasing evidence suggests that sleep alterations could favor subsequent depression development. In order to identify the simultaneous occurrence of these parameters in young people, in this work we evaluated the prevalence of depressive symptoms, sleep habits, and possible sleep disturbances in college students.
Methods:
Beck Depression Inventory (BDI), Epworth Sleepiness Scale (ESS), and a Sleep Habits Questionnaire were applied to students registered at the Autonomous University of Yucatan, Merida (mean age 20.2 +/- 2.6 years). The final sample was composed of 340 (53%) women and 298 (47%) men. Reliability of the BDI and ESS was assessed by Cronbach's alpha method.
Results:
Taking 10 as ESS cut-off point, it was found that 31.6% of the students had a high level of sleepiness. Students with depressive symptoms had a greater number of days with somnolence during class (p <0.05) and perceived that this affected their academic performance at a higher level (p <0.001) than the students without symptoms. In comparison to subjects without depressive symptoms, students with those symptoms rated their sleep quality as poor (p <0.001), perceived a greater latency to initiate sleep after going to bed (p <0.03), and experienced a greater number of awakenings (p <0.04).
Conclusions:
We found diverse sleep alterations in a large proportion of the studied subjects, which were more severe in those who showed depressive symptoms. Educating students for appropriate sleep hygiene and encouraging them to seek professional advice to treat sleep disturbances may be useful to prevent depression.
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