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Prevalence of left ventricular diastolic dysfunction in obese persons with and without diabetes mellitus

Brian Di Stante1, Isaac Galandauer, Wilbert S Aronow

  • 1Department of Medicine, Cardiology Division, New York Medical College, Valhalla, New York 10595, USA.

The American Journal of Cardiology
|June 14, 2005
PubMed

Insights

Obese diabetic patients have significantly higher rates of left ventricular diastolic dysfunction compared to obese non-diabetic patients. This finding highlights the cardiac impact of diabetes in obesity, even before bariatric surgery.

Area of Science:

  • Cardiology
  • Metabolic Disorders
  • Diagnostic Imaging

Background:

  • Obesity is a growing global health concern associated with numerous comorbidities.
  • Diabetes mellitus is a common complication of obesity, increasing cardiovascular risk.
  • Left ventricular diastolic function is a crucial indicator of cardiac health.

Purpose of the Study:

  • To evaluate and compare left ventricular diastolic function in obese diabetic versus obese non-diabetic patients.
  • To determine the prevalence of left ventricular diastolic dysfunction in these populations before gastric bypass surgery.

Main Methods:

  • Doppler and tissue Doppler echocardiography were used to assess diastolic function.
  • The study included 40 obese diabetic and 93 obese non-diabetic patients.
  • Patients underwent echocardiographic evaluation prior to bariatric surgery.

Main Results:

  • Moderate or severe left ventricular diastolic dysfunction was found in 60% of obese diabetics.
  • Only 23% of obese non-diabetics exhibited moderate or severe diastolic dysfunction.
  • The difference in diastolic dysfunction prevalence was statistically significant (p < 0.001).

Conclusions:

  • Obese diabetic patients exhibit a substantially higher prevalence of left ventricular diastolic dysfunction.
  • Diabetes significantly contributes to diastolic cardiac abnormalities in obese individuals.
  • These findings underscore the importance of cardiac assessment in obese diabetic patients.

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