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[Wilson's disease and pregnancy]
V Stvrtinová1, I Balazovjech, S Hlinstáková
1II. interná klinika Lekárskej fakulty UK Bratislava.
Vnitrni Lekarstvi
|March 1, 1992
Summary
Wilson's disease can be successfully managed with penicillamine, allowing women to have healthy pregnancies and infants. Early diagnosis and lifelong treatment prevent severe organ damage, enabling a normal life.
Area of Science:
- Medical Case Study
- Hepatology
- Neurology
Background:
- Wilson's disease is a rare genetic disorder causing copper accumulation in organs.
- Untreated Wilson's disease leads to fatal organ complications, particularly liver and brain damage.
- Effective lifelong treatment is crucial for managing Wilson's disease and preventing morbidity.
Observation:
- A 27-year-old female diagnosed with Wilson's disease was treated with penicillamine.
- Diagnosis was confirmed by Kayser-Fleischer rings and low serum ceruloplasmin (<0.20 g/l).
- The patient became pregnant during penicillamine treatment.
Findings:
- The patient successfully delivered a healthy infant while undergoing penicillamine therapy.
- Penicillamine treatment was effective in managing Wilson's disease during pregnancy.
- No adverse effects on the infant or pregnancy were reported.
Implications:
- This case highlights the safety and efficacy of penicillamine in pregnant women with Wilson's disease.
- Early diagnosis and continuous treatment are vital for women with Wilson's disease to ensure healthy outcomes for both mother and child.
- Effective management allows women with Wilson's disease to lead normal lives and achieve successful pregnancies.